Proteins and dietary fiber are obtained from coconut using membrane separation, centrifugation, twice precipitation technology. Then the bioactive peptides are separated and purified by mixture enzymes and gel chromatography from coconut protein isolates. The results shows that coconut protease hydrolysates with hydrolyzing degree of 14-17.22% have good antioxidant properties. Moreover, coconut peptides with molecular weight of 22.5-31.2 kDa have significant in vitro antihypertensive activity.